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The 86-kD subunit of Ku autoantigen mediates homotypic and heterotypic adhesion of multiple myeloma cells.

Previous studies have shown that triggering multiple myeloma (MM) cells via CD40 induces IL-6-mediated autocrine growth as well as increased expression of cell surface adhesion molecules including CD11a, CD11b, CD11c, and CD18. In this study, we generated the 5E2 mAb which targets an antigen that is...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Teoh, G, Urashima, M, Greenfield, E A, Nguyen, K A, Lee, J F, Chauhan, D, Ogata, A, Treon, S P, Anderson, K C
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508693/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9502780/
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