Novel Catalytically-Inactive PII Metalloproteinases from a Viperid Snake Venom with Substitutions in the Canonical Zinc-Binding Motif

Snake venom metalloproteinases (SVMPs) play key biological roles in prey immobilization and digestion. The majority of these activities depend on the hydrolysis of relevant protein substrates in the tissues. Hereby, we describe several isoforms and a cDNA clone sequence, corresponding to PII SVMP ho...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: Camacho, Erika, Sanz, Libia, Escalante, Teresa, Pérez, Alicia, Villalta, Fabián, Lomonte, Bruno, Neves-Ferreira, Ana Gisele C., Feoli, Andrés, Calvete, Juan J., Gutiérrez, José María, Rucavado, Alexandra
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5086652/
https://ncbi.nlm.nih.gov/pubmed/27754342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins8100292
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