Tissue Localization and Extracellular Matrix Degradation by PI, PII and PIII Snake Venom Metalloproteinases: Clues on the Mechanisms of Venom-Induced Hemorrhage

Snake venom hemorrhagic metalloproteinases (SVMPs) of the PI, PII and PIII classes were compared in terms of tissue localization and their ability to hydrolyze basement membrane components in vivo, as well as by a proteomics analysis of exudates collected in tissue injected with these enzymes. Immun...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Herrera, Cristina, Escalante, Teresa, Voisin, Mathieu-Benoit, Rucavado, Alexandra, Morazán, Diego, Macêdo, Jéssica Kele A., Calvete, Juan J., Sanz, Libia, Nourshargh, Sussan, Gutiérrez, José María, Fox, Jay W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409213/
https://ncbi.nlm.nih.gov/pubmed/25909592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003731
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