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SNAKE VENOMICS OF Crotalus tigris: THE MINIMALIST TOXIN ARSENAL OF THE DEADLIEST NEARTIC RATTLESNAKE VENOM: Evolutionary clues for generating a pan-specific antivenom against crotalid type II venoms

We report the proteomic and antivenomic characterization of Crotalus tigris venom. This venom exhibits the highest lethality for mice among rattlesnakes and the simplest toxin proteome reported to date. The venom proteome of C. tigris comprises 7–8 gene products from 6 toxin families: the presynapti...

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Detalhes bibliográficos
Main Authors: CALVETE, Juan J., PÉREZ, Alicia, LOMONTE, Bruno, SÁNCHEZ, Elda E., SANZ, Libia
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272105/
https://ncbi.nlm.nih.gov/pubmed/22181673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr201021d
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