Elevated Hypothalamic Glucocorticoid Levels Are Associated With Obesity and Hyperphagia in Male Mice

Glucocorticoid (Gc) excess, from endogenous overproduction in disorders of the hypothalamic-pituitary-adrenal axis or exogenous medical therapy, is recognized to cause adverse metabolic side effects. The Gc receptor (GR) is widely expressed throughout the body, including brain regions such as the hy...

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Опубликовано в: :Endocrinology
Главные авторы: Sefton, Charlotte, Harno, Erika, Davies, Alison, Small, Helen, Allen, Tiffany-Jayne, Wray, Jonathan R., Lawrence, Catherine B., Coll, Anthony P., White, Anne
Формат: Artigo
Язык:Inglês
Опубликовано: Endocrine Society 2016
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Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5086535/
https://ncbi.nlm.nih.gov/pubmed/27649090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2016-1571
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