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Genetic polymorphisms in 5-FU related enzymes predict pathologic response following neoadjuvant chemoradiation for rectal cancer
BACKGROUND: Patients with rectal cancer undergo preoperative neoadjuvant chemoradiation with approximately 70% exhibiting pathologic down-staging in response to treatment. There is currently no accurate test to predict patients who are likely to be complete responders to therapy. 5-Fluorouracil (5-F...
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| Veröffentlicht in: | Surgery |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5086288/ https://ncbi.nlm.nih.gov/pubmed/27423551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2016.05.017 |
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