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Genetic polymorphisms in 5-FU related enzymes predict pathologic response following neoadjuvant chemoradiation for rectal cancer

BACKGROUND: Patients with rectal cancer undergo preoperative neoadjuvant chemoradiation with approximately 70% exhibiting pathologic down-staging in response to treatment. There is currently no accurate test to predict patients who are likely to be complete responders to therapy. 5-Fluorouracil (5-F...

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Detalhes bibliográficos
Publicado no:Surgery
Main Authors: Nelson, Bailey, Carter, Jane V., Eichenberger, Maurice R., Netz, Uri, Galandiuk, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5086288/
https://ncbi.nlm.nih.gov/pubmed/27423551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2016.05.017
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