Expression of CD4 in transgenic mice alters the specificity of CD8 cells for allogeneic major histocompatibility complex.

We have generated a transgenic mouse line in which a CD4 transgene is expressed on a significant fraction of the mature CD8+ lymphocytes but is not expressed in the thymus. This provides an opportunity to examine the functional consequences of CD4 expression in a population of class I-selected CD8+...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Robey, E, Ramsdell, F, Elliott, J, Raulet, D, Kioussis, D, Axel, R, Fowlkes, B J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1991
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50861/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1824875/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.2.608
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!