Mice lacking major histocompatibility complex class I and class II molecules.

Mice lacking major histocompatibility complex (MHC) antigens were generated by mating beta 2-microglobulin-deficient, and therefore class I-deficient, animals with MHC class II-deficient animals. When housed under sterile conditions, the resulting MHC-deficient mice appear healthy, survive for many...

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Detalhes bibliográficos
Main Authors: Grusby, M J, Auchincloss, H, Lee, R, Johnson, R S, Spencer, J P, Zijlstra, M, Jaenisch, R, Papaioannou, V E, Glimcher, L H
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC46416/
https://ncbi.nlm.nih.gov/pubmed/8483910
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