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A combination therapy for KRAS-mutant lung cancer by targeting synthetic lethal partners of mutant KRAS

The KRAS gene is frequently mutated in multiple cancer types, but it fell off the drug discovery radar for many years because of its inherent “undruggable” structure and undefined biological properties. As reported in the paper entitled “Suppression of KRas-mutant cancer through the combined inhibit...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Chin J Cancer
Egile Nagusiak: Pang, Xiufeng, Liu, Mingyao
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5086049/
https://ncbi.nlm.nih.gov/pubmed/27793187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40880-016-0154-7
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