Cardiac muscarinic receptors decrease with age. In vitro and in vivo studies.

The M1 muscarinic receptor antagonist pirenzepine in low doses decreases resting heart rate; this effect declines with age (Poller, U., G. Nedelka, J. Radke, K. Pönicke, and O.-E. Brodde. 1997. J. Am. Coll. Cardiol. 29:187-193). To study possible mechanisms underlying this effect, we assessed (a) in...

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Main Authors: Brodde, O E, Konschak, U, Becker, K, Rüter, F, Poller, U, Jakubetz, J, Radke, J, Zerkowski, H R
Formato: Artigo
Idioma:Inglês
Publicado: 1998
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC508587/
https://ncbi.nlm.nih.gov/pubmed/9435320
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