Age-dependent decrease in the affinity of muscarinic M1 receptors in neocortex of rhesus monkeys.
In vitro autoradiography on tissue sections and receptor assay in cortical membrane homogenates revealed that pirenzepine high-affinity muscarinic sites (M1) decrease in affinity in the prefrontal cortex and in other cortical areas of aged rhesus monkey (Macaca mulatta). Carbachol competition experi...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53158/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1763062/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.24.11475 |
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