Homeodomain-Interacting Protein Kinase-2: A Critical Regulator of the DNA Damage Response and the Epigenome

Homeodomain-interacting protein kinase 2 (HIPK2) is a serine/threonine kinase that phosphorylates and activates the apoptotic program through interaction with diverse downstream targets including tumor suppressor p53. HIPK2 is activated by genotoxic stimuli and modulates cell fate following DNA dama...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Mol Sci
Prif Awduron: Kuwano, Yuki, Nishida, Kensei, Akaike, Yoko, Kurokawa, Ken, Nishikawa, Tatsuya, Masuda, Kiyoshi, Rokutan, Kazuhito
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2016
Pynciau:
Review
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085671/
https://ncbi.nlm.nih.gov/pubmed/27689990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17101638
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