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Homeodomain-Interacting Protein Kinase-2: A Critical Regulator of the DNA Damage Response and the Epigenome

Homeodomain-interacting protein kinase 2 (HIPK2) is a serine/threonine kinase that phosphorylates and activates the apoptotic program through interaction with diverse downstream targets including tumor suppressor p53. HIPK2 is activated by genotoxic stimuli and modulates cell fate following DNA dama...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kuwano, Yuki, Nishida, Kensei, Akaike, Yoko, Kurokawa, Ken, Nishikawa, Tatsuya, Masuda, Kiyoshi, Rokutan, Kazuhito
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085671/
https://ncbi.nlm.nih.gov/pubmed/27689990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17101638
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