Homeodomain-Interacting Protein Kinase-2: A Critical Regulator of the DNA Damage Response and the Epigenome

Homeodomain-interacting protein kinase 2 (HIPK2) is a serine/threonine kinase that phosphorylates and activates the apoptotic program through interaction with diverse downstream targets including tumor suppressor p53. HIPK2 is activated by genotoxic stimuli and modulates cell fate following DNA dama...

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Publicat a:Int J Mol Sci
Autors principals: Kuwano, Yuki, Nishida, Kensei, Akaike, Yoko, Kurokawa, Ken, Nishikawa, Tatsuya, Masuda, Kiyoshi, Rokutan, Kazuhito
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2016
Matèries:
Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085671/
https://ncbi.nlm.nih.gov/pubmed/27689990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17101638
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