Homeodomain-Interacting Protein Kinase-2: A Critical Regulator of the DNA Damage Response and the Epigenome

Homeodomain-interacting protein kinase 2 (HIPK2) is a serine/threonine kinase that phosphorylates and activates the apoptotic program through interaction with diverse downstream targets including tumor suppressor p53. HIPK2 is activated by genotoxic stimuli and modulates cell fate following DNA dama...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Kuwano, Yuki, Nishida, Kensei, Akaike, Yoko, Kurokawa, Ken, Nishikawa, Tatsuya, Masuda, Kiyoshi, Rokutan, Kazuhito
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2016
Teme:
Review
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085671/
https://ncbi.nlm.nih.gov/pubmed/27689990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17101638
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