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Low-dose IL-2 selectively activates subsets of CD4(+) Tregs and NK cells
CD4(+) regulatory T cells (CD4Tregs) play a critical role in the maintenance of immune tolerance and prevention of chronic graft-versus-host disease (GVHD) after allogeneic hematopoietic stem cell transplantation. IL-2 supports the proliferation and survival of CD4Tregs and previous studies have dem...
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| Publicat a: | JCI Insight |
|---|---|
| Autors principals: | , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5085610/ https://ncbi.nlm.nih.gov/pubmed/27812545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.89278 |
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