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Low-dose IL-2 selectively activates subsets of CD4(+) Tregs and NK cells

CD4(+) regulatory T cells (CD4Tregs) play a critical role in the maintenance of immune tolerance and prevention of chronic graft-versus-host disease (GVHD) after allogeneic hematopoietic stem cell transplantation. IL-2 supports the proliferation and survival of CD4Tregs and previous studies have dem...

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Dades bibliogràfiques
Publicat a:JCI Insight
Autors principals: Hirakawa, Masahiro, Matos, Tiago, Liu, Hongye, Koreth, John, Kim, Haesook T., Paul, Nicole E., Murase, Kazuyuki, Whangbo, Jennifer, Alho, Ana C., Nikiforow, Sarah, Cutler, Corey, Ho, Vincent T., Armand, Philippe, Alyea, Edwin P., Antin, Joseph H., Blazar, Bruce R., Lacerda, Joao F., Soiffer, Robert J., Ritz, Jerome
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085610/
https://ncbi.nlm.nih.gov/pubmed/27812545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.89278
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