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Unbalanced recovery of regulatory and effector T cells after allogeneic stem cell transplantation contributes to chronic GVHD

The development and maintenance of immune tolerance after allogeneic hematopoietic stem cell transplantation (HSCT) requires the balanced reconstitution of donor-derived CD4 regulatory T cells (CD4Tregs) as well as effector CD4 (conventional CD4 T cells [CD4Tcons]) and CD8 T cells. To characterize t...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Alho, Ana C., Kim, Haesook T., Chammas, Marie J., Reynolds, Carol G., Matos, Tiago R., Forcade, Edouard, Whangbo, Jennifer, Nikiforow, Sarah, Cutler, Corey S., Koreth, John, Ho, Vincent T., Armand, Philippe, Antin, Joseph H., Alyea, Edwin P., Lacerda, Joao F., Soiffer, Robert J., Ritz, Jerome
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742552/
https://ncbi.nlm.nih.gov/pubmed/26670634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-10-672345
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