Unbalanced recovery of regulatory and effector T cells after allogeneic stem cell transplantation contributes to chronic GVHD

The development and maintenance of immune tolerance after allogeneic hematopoietic stem cell transplantation (HSCT) requires the balanced reconstitution of donor-derived CD4 regulatory T cells (CD4Tregs) as well as effector CD4 (conventional CD4 T cells [CD4Tcons]) and CD8 T cells. To characterize t...

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Vydáno v:Blood
Hlavní autoři: Alho, Ana C., Kim, Haesook T., Chammas, Marie J., Reynolds, Carol G., Matos, Tiago R., Forcade, Edouard, Whangbo, Jennifer, Nikiforow, Sarah, Cutler, Corey S., Koreth, John, Ho, Vincent T., Armand, Philippe, Antin, Joseph H., Alyea, Edwin P., Lacerda, Joao F., Soiffer, Robert J., Ritz, Jerome
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2016
Témata:
Transplantation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742552/
https://ncbi.nlm.nih.gov/pubmed/26670634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-10-672345
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