Acquired platinum resistance involves epithelial to mesenchymal transition through ubiquitin ligase FBXO32 dysregulation

To identify the molecules involved in epithelial to mesenchymal transition (EMT) in urothelial carcinoma (UC) after acquisition of platinum resistance, here we examined the changes in global gene expression before and after platinum treatment. Four invasive UC cell lines, T24, 5637, and their corres...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Tanaka, Nobuyuki, Kosaka, Takeo, Miyazaki, Yasumasa, Mikami, Shuji, Niwa, Naoya, Otsuka, Yutaro, Minamishima, Yoji Andrew, Mizuno, Ryuichi, Kikuchi, Eiji, Miyajima, Akira, Sabe, Hisataka, Okada, Yasunori, Uhlén, Per, Suematsu, Makoto, Oya, Mototsugu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085609/
https://ncbi.nlm.nih.gov/pubmed/27812537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.83654
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