Single‐cell RNA‐seq analysis reveals the platinum resistance gene COX7B and the surrogate marker CD63

Cancers acquire resistance to systemic treatment with platinum‐based chemotherapy (eg, cisplatin [CDDP]) as a result of a dynamic intratumoral heterogeneity (ITH) and clonal repopulation. However, little is known about the influence of chemotherapy on ITH at the single‐cell level. Here, mapping the...

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Bibliografische gegevens
Gepubliceerd in:Cancer Med
Hoofdauteurs: Tanaka, Nobuyuki, Katayama, Shintaro, Reddy, Aparna, Nishimura, Kaneyasu, Niwa, Naoya, Hongo, Hiroshi, Ogihara, Koichiro, Kosaka, Takeo, Mizuno, Ryuichi, Kikuchi, Eiji, Mikami, Shuji, Miyakawa, Ayako, Arenas, Ernest, Kere, Juha, Oya, Mototsugu, Uhlén, Per
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2018
Onderwerpen:
Cancer Biology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6308066/
https://ncbi.nlm.nih.gov/pubmed/30367559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1828
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