Down-regulation of NF kappa B activation is an effective therapeutic modality in acquired platinum-resistant bladder cancer

BACKGROUND: No previous study has addressed the efficacy of NF-κB blockade when bladder tumors develop acquired resistance toward CDDP-treatments. We investigated the changes in NF-κB activation and therapeutic impact of NF-κB blockade by the novel NF-κB inhibitor dehydroxymethyl derivative of epoxy...

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Publicat a:BMC Cancer
Autors principals: Ito, Yujiro, Kikuchi, Eiji, Tanaka, Nobuyuki, Kosaka, Takeo, Suzuki, Eriko, Mizuno, Ryuichi, Shinojima, Toshiaki, Miyajima, Akira, Umezawa, Kazuo, Oya, Mototsugu
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424446/
https://ncbi.nlm.nih.gov/pubmed/25926105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1315-9
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