An apolipoprotein E synthetic peptide targets to lipoproteins in plasma and mediates both cellular lipoprotein interactions in vitro and acute clearance of cholesterol-rich lipoproteins in vivo.

Apolipoprotein (apo) E mediates lipoprotein binding to cellular lipoprotein receptors. Previously we reported that a synthetic peptide representing a linear dimeric repeat of amino acids 141-155 binds cellular LDL receptors. To prepare an apoE peptide that bound to both cholesterol-rich lipoproteins...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Nikoulin, I R, Curtiss, L K
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 1998
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508559/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9421485/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI1099
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