Intravenous infusion of apolipoprotein E accelerates clearance of plasma lipoproteins in rabbits.

Plasma cholesterol levels in cholesterol-fed rabbits were markedly reduced by the intravenous infusion or bolus injection of recombinant human apo E or rabbit plasma apo E. Administration of 6-70 mg of apo E resulted in an approximately 20-40% acute reduction in plasma cholesterol levels within 2-3...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Mahley, R W, Weisgraber, K H, Hussain, M M, Greenman, B, Fisher, M, Vogel, T, Gorecki, M
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303940/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2723074/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114126
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