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Hyperplasia and hypertrophy of pulmonary neuroepithelial bodies, presumed airway hypoxia sensors, in hypoxia-inducible factor prolyl hydroxylase-deficient mice

Pulmonary neuroepithelial bodies (NEBs), presumed polymodal airway sensors, consist of innervated clusters of amine (serotonin) and peptide-producing cells. While NEB responses to acute hypoxia are mediated by a membrane-bound O(2) sensor complex, responses to sustained and/or chronic hypoxia involv...

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Publicat a:Hypoxia (Auckl)
Autors principals: Pan, Jie, Bishop, Tammie, Ratcliffe, Peter J, Yeger, Herman, Cutz, Ernest
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085281/
https://ncbi.nlm.nih.gov/pubmed/27800509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/HP.S103957
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