Neoadjuvant tamoxifen synchronizes ERα binding and gene expression profiles related to outcome and proliferation

Estrogen receptor alpha (ERα)-positive breast cancers are frequently treated with tamoxifen, but resistance is common. It remains elusive how tamoxifen resistance occurs and predictive biomarkers for treatment outcome are needed. Because most biomarker discovery studies are performed using pre-treat...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Severson, Tesa M., Nevedomskaya, Ekaterina, Peeters, Justine, Kuilman, Thomas, Krijgsman, Oscar, van Rossum, Annelot, Droog, Marjolein, Kim, Yongsoo, Koornstra, Rutger, Beumer, Inès, Glas, Annuska M., Peeper, Daniel, Wesseling, Jelle, Simon, Iris M., Wessels, Lodewyk, Linn, Sabine C., Zwart, Wilbert
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085127/
https://ncbi.nlm.nih.gov/pubmed/27129152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8983
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