Somatic Mutations Modulate Autoantibodies against Galactose-Deficient IgA1 in IgA Nephropathy

Autoantibodies against galactose-deficient IgA1 drive formation of pathogenic immune complexes in IgA nephropathy. IgG autoantibodies against galactose-deficient IgA1 in patients with IgA nephropathy have a specific amino-acid sequence, Y(1)CS(3), in the complementarity-determining region 3 of the h...

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Dades bibliogràfiques
Publicat a:J Am Soc Nephrol
Autors principals: Huang, Zhi Qiang, Raska, Milan, Stewart, Tyler J., Reily, Colin, King, R. Glenn, Crossman, David K., Crowley, Michael R., Hargett, Audra, Zhang, Zhixin, Suzuki, Hitoshi, Hall, Stacy, Wyatt, Robert J., Julian, Bruce A., Renfrow, Matthew B., Gharavi, Ali G., Novak, Jan
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2016
Matèries:
Brief Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084875/
https://ncbi.nlm.nih.gov/pubmed/26966014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014101044
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