Somatic Mutations Modulate Autoantibodies against Galactose-Deficient IgA1 in IgA Nephropathy

Autoantibodies against galactose-deficient IgA1 drive formation of pathogenic immune complexes in IgA nephropathy. IgG autoantibodies against galactose-deficient IgA1 in patients with IgA nephropathy have a specific amino-acid sequence, Y(1)CS(3), in the complementarity-determining region 3 of the h...

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Bibliografische gegevens
Gepubliceerd in:J Am Soc Nephrol
Hoofdauteurs: Huang, Zhi Qiang, Raska, Milan, Stewart, Tyler J., Reily, Colin, King, R. Glenn, Crossman, David K., Crowley, Michael R., Hargett, Audra, Zhang, Zhixin, Suzuki, Hitoshi, Hall, Stacy, Wyatt, Robert J., Julian, Bruce A., Renfrow, Matthew B., Gharavi, Ali G., Novak, Jan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Nephrology 2016
Onderwerpen:
Brief Communications
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084875/
https://ncbi.nlm.nih.gov/pubmed/26966014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014101044
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