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Galactose-deficient IgA1 and the corresponding IgG autoantibodies predict IgA nephropathy progression

BACKGROUND: IgA nephropathy (IgAN), the most common primary glomerulonephritis worldwide, has serious outcomes with end-stage renal disease developing in 30–50% of patients. The diagnosis requires renal biopsy. Due to its inherent risks, non-invasive approaches are needed. METHODS: We evaluated 91 C...

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Veröffentlicht in:PLoS One
Hauptverfasser: Maixnerova, Dita, Ling, Chunyan, Hall, Stacy, Reily, Colin, Brown, Rhubell, Neprasova, Michaela, Suchanek, Miloslav, Honsova, Eva, Zima, Tomas, Novak, Jan, Tesar, Vladimir
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6386256/
https://ncbi.nlm.nih.gov/pubmed/30794576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0212254
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