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FBXW7 is involved in the acquisition of the malignant phenotype in epithelial ovarian tumors
FBXW7 is a ubiquitin ligase that mediates ubiquitylation of oncoproteins, such as c‐Myc, cyclin E, Notch and c‐Jun. FBXW7 is a known tumor‐suppressor gene, and mutations in FBXW7 have been reported in various human malignancies. In this study, we examined the sequences of the FBXW7 and p53 genes in...
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| Publicat a: | Cancer Sci |
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| Autors principals: | , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5084658/ https://ncbi.nlm.nih.gov/pubmed/27486687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13026 |
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