SNP55, a new functional polymorphism of MDM2-P2 promoter, contributes to allele-specific expression of MDM2 in endometrial cancers

BACKGROUND: The functional single nucleotide polymorphism (SNP) in the MDM2 promoter region, SNP309, is known to be associated with various diseases, particularly cancer. Although many studies have been performed to demonstrate the mechanism of allele-specific expression (ASE) on SNP309, they have o...

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Detalhes bibliográficos
Publicado no:BMC Med Genet
Main Authors: Okamoto, Kanako, Tsunematsu, Ryosuke, Tahira, Tomoko, Sonoda, Kenzo, Asanoma, Kazuo, Yagi, Hiroshi, Yoneda, Tomoko, Hayashi, Kenshi, Wake, Norio, Kato, Kiyoko
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593204/
https://ncbi.nlm.nih.gov/pubmed/26293665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-015-0216-8
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