Genetic and Pharmacologic Inhibition of the Chemokine Receptor CXCR2 Prevents Experimental Hypertension and Vascular Dysfunction

BACKGROUND: The recruitment of leukocytes to the vascular wall is a key step in hypertension development. Chemokine receptor CXCR2 mediates inflammatory cell chemotaxis in several diseases. However, the role of CXCR2 in hypertension development and the underlying mechanisms remain unknown. METHODS:...

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Detalhes bibliográficos
Publicado no:Circulation
Main Authors: Wang, Lei, Zhao, Xue-Chen, Cui, Wei, Ma, Yong-Qiang, Ren, Hua-Liang, Zhou, Xin, Fassett, John, Yang, Yan-Zong, Chen, Yingjie, Xia, Yun-Long, Du, Jie, Li, Hui-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2016
Assuntos:
Original Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084654/
https://ncbi.nlm.nih.gov/pubmed/27678262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.115.020754
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