Transgenic expression of the human amphiregulin gene induces a psoriasis-like phenotype.

Amphiregulin (AR) is a heparin-binding, heparin-inhibited member of the epidermal growth factor (EGF) family and an autocrine growth factor for human keratinocytes. Previous studies have shown that AR expression is increased in psoriatic epidermis. To test the hypothesis that aberrant AR expression...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Cook, P W, Piepkorn, M, Clegg, C H, Plowman, G D, DeMay, J M, Brown, J R, Pittelkow, M R
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508424/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9410906/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119766
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