Doxycycline-Induced Expression of Transgenic Human Tumor Necrosis Factor α in Adult Mice Results in Psoriasis-like Arthritis

OBJECTIVE: To generate doxycycline-inducible human tumor necrosis factor α (TNFα)–transgenic mice to overcome a major disadvantage of existing transgenic mice with constitutive expression of TNFα, which is the limitation in crossing them with various knockout or transgenic mice. METHODS: A transgeni...

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Detalhes bibliográficos
Main Authors: Retser, Eugen, Schied, Tanja, Skryabin, Boris V, Vogl, Thomas, Kanczler, Janos M, Hamann, Nina, Niehoff, Anja, Hermann, Sven, Eisenblätter, Michel, Wachsmuth, Lydia, Pap, Thomas, van Lent, Peter L E M, Loser, Karin, Roth, Johannes, Zaucke, Frank, Ludwig, Stephan, Wixler, Viktor
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Experimental Arthritis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798087/
https://ncbi.nlm.nih.gov/pubmed/23740547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38026
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