Inflammatory Cytokines Stabilize SOXC Transcription Factors to Mediate the Transformation of Fibroblast‐Like Synoviocytes in Arthritic Disease

OBJECTIVE: Fibroblast‐like synoviocytes (FLS) produce key synovial fluid and tissue components to ensure joint integrity under healthy conditions, whereas they become cancer‐like and aggressively contribute to joint degeneration in inflammatory arthritis. The aim of this study was to determine wheth...

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Bibliografiske detaljer
Udgivet i:Arthritis Rheumatol
Main Authors: Bhattaram, Pallavi, Muschler, George, Wixler, Viktor, Lefebvre, Véronique
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Rheumatoid Arthritis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826855/
https://ncbi.nlm.nih.gov/pubmed/29193895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40386
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