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Transgenic expression of the human amphiregulin gene induces a psoriasis-like phenotype.

Amphiregulin (AR) is a heparin-binding, heparin-inhibited member of the epidermal growth factor (EGF) family and an autocrine growth factor for human keratinocytes. Previous studies have shown that AR expression is increased in psoriatic epidermis. To test the hypothesis that aberrant AR expression...

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Detalhes bibliográficos
Main Authors: Cook, P W, Piepkorn, M, Clegg, C H, Plowman, G D, DeMay, J M, Brown, J R, Pittelkow, M R
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC508424/
https://ncbi.nlm.nih.gov/pubmed/9410906
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