Transgenic expression of the human amphiregulin gene induces a psoriasis-like phenotype.

Amphiregulin (AR) is a heparin-binding, heparin-inhibited member of the epidermal growth factor (EGF) family and an autocrine growth factor for human keratinocytes. Previous studies have shown that AR expression is increased in psoriatic epidermis. To test the hypothesis that aberrant AR expression...

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Détails bibliographiques
Auteurs principaux: Cook, P W, Piepkorn, M, Clegg, C H, Plowman, G D, DeMay, J M, Brown, J R, Pittelkow, M R
Format: Artigo
Langue:Inglês
Publié: 1997
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC508424/
https://ncbi.nlm.nih.gov/pubmed/9410906
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