Transgenic expression of the human amphiregulin gene induces a psoriasis-like phenotype.

Amphiregulin (AR) is a heparin-binding, heparin-inhibited member of the epidermal growth factor (EGF) family and an autocrine growth factor for human keratinocytes. Previous studies have shown that AR expression is increased in psoriatic epidermis. To test the hypothesis that aberrant AR expression...

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Cook, P W, Piepkorn, M, Clegg, C H, Plowman, G D, DeMay, J M, Brown, J R, Pittelkow, M R
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1997
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508424/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9410906/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119766
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