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Intraventricular and intracerebral delivery of anti-epileptic drugs in the kindling model
A means to avoid the pharmacokinetic problems affecting the anti-epileptic drugs may be their direct intracerebroventricular (ICV) or intracerebral delivery. This approach may achieve a greater drug concentration at the epileptogenic area while minimizing it in other brain or systemic areas, and thu...
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| Publicado en: | Neurotherapeutics |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Springer-Verlag
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5084212/ https://ncbi.nlm.nih.gov/pubmed/19332328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nurt.2009.01.015 |
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