Envelope glycoproteins from biologically diverse isolates of immunodeficiency viruses have widely different affinities for CD4.

The envelope glycoprotein gp120 of primate immunodeficiency viruses initiates viral attachment to CD4+ cells by binding to the CD4 antigen on host cell surfaces. However, among different CD4+ cell types, different viruses display distinct host cell ranges and cytopathicities. Determinants for both o...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Ivey-Hoyle, M, Culp, J S, Chaikin, M A, Hellmig, B D, Matthews, T J, Sweet, R W, Rosenberg, M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50841/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1899141/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.2.512
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