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Envelope glycoproteins from biologically diverse isolates of immunodeficiency viruses have widely different affinities for CD4.

The envelope glycoprotein gp120 of primate immunodeficiency viruses initiates viral attachment to CD4+ cells by binding to the CD4 antigen on host cell surfaces. However, among different CD4+ cell types, different viruses display distinct host cell ranges and cytopathicities. Determinants for both o...

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Autors principals: Ivey-Hoyle, M, Culp, J S, Chaikin, M A, Hellmig, B D, Matthews, T J, Sweet, R W, Rosenberg, M
Format: Artigo
Idioma:Inglês
Publicat: 1991
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC50841/
https://ncbi.nlm.nih.gov/pubmed/1899141
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