The RIG-I-like helicase receptor MDA5 (IFIH1) is involved in the host defense against Candida infections

The induction of host defense against Candida species is initiated by recognition of the fungi by pattern recognition receptors and activation of downstream pathways that produce inflammatory mediators essential for infection clearance. In the present study, we present complementary evidence based o...

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Udgivet i:Eur J Clin Microbiol Infect Dis
Main Authors: Jaeger, Martin, van der Lee, Robin, Cheng, Shih-Chin, Johnson, Melissa D., Kumar, Vinod, Ng, Aylwin, Plantinga, Theo S., Smeekens, Sanne P., Oosting, Marije, Wang, Xinhui, Barchet, Winfried, Fitzgerald, Kate, Joosten, Leo A.B., Perfect, John R., Wijmenga, Cisca, van de Veerdonk, Frank L., Huynen, Martijn A., Xavier, Ramnik J., Kullberg, Bart-Jan, Netea, Mihai G.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084092/
https://ncbi.nlm.nih.gov/pubmed/25579795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10096-014-2309-2
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