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Solution NMR Studies of an Alternative Mode of Sin3 Engagement by the Sds3 Subunit in the Histone Deacetylase-Associated Sin3L/Rpd3L Corepressor Complex

The Sds3 transcriptional corepressor facilitates the assembly of the 1-2 megadalton histone deacetylase (HDAC)-associated Sin3L/Rpd3L complex by providing a crucial homo-dimerization activity. Sds3 engages the scaffolding protein Sin3A, via a bipartite motif within the Sin3 interaction domain (SID)...

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Detalles Bibliográficos
Publicado en:J Mol Biol
Autores principales: Clark, Michael David, Zhang, Yongbo, Radhakrishnan, Ishwar
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084087/
https://ncbi.nlm.nih.gov/pubmed/26522936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.10.018
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