Sequence Requirements for Combinatorial Recognition of Histone H3 by the MRG15 and Pf1 Subunits of the Rpd3S/Sin3S Corepressor Complex

The transcriptional output at a genomic locus in eukaryotes is determined, in part, by the pattern of histone modifications that are read and interpreted by key effector proteins. The histone deacetylase activity of the evolutionarily-conserved Rpd3S/Sin3S complex is crucial for suppressing aberrant...

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Bibliographic Details
Main Authors: Kumar, Ganesan Senthil, Chang, William, Xie, Tao, Patel, Anand, Zhang, Yongbo, Wang, Gang Greg, David, Gregory, Radhakrishnan, Ishwar
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428507/
https://ncbi.nlm.nih.gov/pubmed/22728643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.06.013
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