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Solution Structure of the mSin3A PAH2-Pf1 SID1 Complex: a Mad1/Mxd1-like Interaction Disrupted by MRG15 in the Rpd3S/Sin3S Complex

Histone deacetylation constitutes an important mechanism for silencing genes. The HDAC-associated mammalian Rpd3S/Sin3S corepressor complex plays key roles in repressing aberrant gene transcription from cryptic transcription initiation sites and mitigating RNA polymerase II progression in intragenic...

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Detalhes bibliográficos
Main Authors: Kumar, Ganesan Senthil, Xie, Tao, Zhang, Yongbo, Radhakrishnan, Ishwar
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096069/
https://ncbi.nlm.nih.gov/pubmed/21440557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.03.043
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