The Identification of Biochanin A as a Potent and Selective β-Site App-Cleaving Enzyme 1 (Bace1) Inhibitor

Beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) is the enzyme involved in the abnormal production of the amyloidogenic peptide Aβ, one of the major causes of histological hallmarks of Alzheimer’s disease (AD). Thus, BACE1 represents a key target protein in the development of new potent...

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Bibliografische gegevens
Gepubliceerd in:Nutrients
Hoofdauteurs: Youn, Kumju, Park, Ji-Hyun, Lee, Jinhyuk, Jeong, Woo-Sik, Ho, Chi-Tang, Jun, Mira
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2016
Onderwerpen:
Communication
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084024/
https://ncbi.nlm.nih.gov/pubmed/27754406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu8100637
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