Effects of an oral iron chelator, deferasirox, on advanced hepatocellular carcinoma

AIM: To evaluate the inhibitory effects of deferasirox (DFX) against hepatocellular carcinoma (HCC) through basic and clinical studies. METHODS: In the basic study, the effect of DFX was investigated in three hepatoma cell lines (HepG2, Hep3B, and Huh7), as well as in an N-nitrosodiethylamine-induce...

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Bibliografiske detaljer
Udgivet i:World J Gastroenterol
Main Authors: Saeki, Issei, Yamamoto, Naoki, Yamasaki, Takahiro, Takami, Taro, Maeda, Masaki, Fujisawa, Koichi, Iwamoto, Takuya, Matsumoto, Toshihiko, Hidaka, Isao, Ishikawa, Tsuyoshi, Uchida, Koichi, Tani, Kenji, Sakaida, Isao
Format: Artigo
Sprog:Inglês
Udgivet: Baishideng Publishing Group Inc 2016
Fag:
Clinical Trials Study
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5083802/
https://ncbi.nlm.nih.gov/pubmed/27833388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v22.i40.8967
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