Oral magnesium supplements reduce erythrocyte dehydration in patients with sickle cell disease.

Intracellular polymerization and sickling depend markedly on the cellular concentration of sickle hemoglobin (Hb S). A possible therapeutic strategy for sickle cell disease is based on reducing the cellular concentration of Hb S through prevention of erythrocyte dehydration. The K-Cl cotransporter i...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: De Franceschi, L, Bachir, D, Galacteros, F, Tchernia, G, Cynober, T, Alper, S, Platt, O, Beuzard, Y, Brugnara, C
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1997
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508371/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9312186/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119713
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