Suppression of transcription factor PDX-1/IPF1/STF-1/IDX-1 causes no decrease in insulin mRNA in MIN6 cells.

The insulin gene transcription factor PDX-1/IPF1/STF-1/ IDX-1 plays a key role in directing beta cell-specific gene expressions. Recently, impairment of PDX-1 expression or activity has been observed in beta cell-derived HIT cells cultured under high glucose concentrations, and this has been suggest...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Kajimoto, Y, Watada, H, Matsuoka, T a, Kaneto, H, Fujitani, Y, Miyazaki, J, Yamasaki, Y
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1997
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508370/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9312185/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119712
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