Leukocyte adhesion deficiency type 1 (LAD-1)/variant. A novel immunodeficiency syndrome characterized by dysfunctional beta2 integrins.

Leukocyte adhesion deficiency (LAD) is characterized by the inability of leukocytes, in particular neutrophilic granulocytes, to emigrate from the bloodstream towards sites of inflammation. Infectious foci are nonpurulent and may eventually become necrotic because of abnormal wound healing. LAD-1 is...

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Dettagli Bibliografici
Autori principali: Kuijpers, T W, Van Lier, R A, Hamann, D, de Boer, M, Thung, L Y, Weening, R S, Verhoeven, A J, Roos, D
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1997
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC508355/
https://ncbi.nlm.nih.gov/pubmed/9312170
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