Leukocyte adhesion deficiency type 1 (LAD-1)/variant. A novel immunodeficiency syndrome characterized by dysfunctional beta2 integrins.

Leukocyte adhesion deficiency (LAD) is characterized by the inability of leukocytes, in particular neutrophilic granulocytes, to emigrate from the bloodstream towards sites of inflammation. Infectious foci are nonpurulent and may eventually become necrotic because of abnormal wound healing. LAD-1 is...

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Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: Kuijpers, T W, Van Lier, R A, Hamann, D, de Boer, M, Thung, L Y, Weening, R S, Verhoeven, A J, Roos, D
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 1997
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508355/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9312170/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119697
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