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Ventilation and oxygenation induce endothelial nitric oxide synthase gene expression in the lungs of fetal lambs.

At birth, ventilation and oxygenation immediately decrease pulmonary vascular resistance (PVR) and increase pulmonary blood flow (PBF); more gradual changes occur over the next several hours. Nitric oxide, produced by endothelial nitric oxide synthase (eNOS), mediates these gradual changes. To deter...

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Bibliographische Detailangaben
Hauptverfasser: Black, S M, Johengen, M J, Ma, Z D, Bristow, J, Soifer, S J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1997
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC508323/
https://ncbi.nlm.nih.gov/pubmed/9294110
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