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Ventilation and oxygenation induce endothelial nitric oxide synthase gene expression in the lungs of fetal lambs.

At birth, ventilation and oxygenation immediately decrease pulmonary vascular resistance (PVR) and increase pulmonary blood flow (PBF); more gradual changes occur over the next several hours. Nitric oxide, produced by endothelial nitric oxide synthase (eNOS), mediates these gradual changes. To deter...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Black, S M, Johengen, M J, Ma, Z D, Bristow, J, Soifer, S J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508323/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9294110/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119665
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