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Effects of Hemin on Heme Oxygenase-1, Gastric Emptying, and Symptoms in Diabetic Gastroparesis

BACKGROUND: Therapeutic options for management of diabetic gastroparesis are limited. Failure to maintain upregulation of heme oxygenase (HO1) leads to loss of interstitial cells of Cajal and delayed gastric emptying in non-obese diabetic (NOD) mice. Our hypothesis was that hemin upregulation of HO1...

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Publicado en:Neurogastroenterol Motil
Main Authors: Bharucha, Adil E., Daley, Shannon L., Low, Phillip A, Gibbons, Simon J., Choi, Kyoung Moo, Camilleri, Michael, Saw, essica J., Farrugia, Gianrico, Zinsmeister, Alan R
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5083191/
https://ncbi.nlm.nih.gov/pubmed/27283929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nmo.12874
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