FIRST-IN-HUMAN STUDY DEMONSTRATING PHARMACOLOGICAL ACTIVATION OF HEME OXYGENASE-1 IN HUMANS

Heme-oxygenase 1 (HO-1) degrades heme and protects against oxidative stress, but has not been pharmacologically induced in humans. In this randomized study (10 healthy volunteers), hemin (3 mg/kg. i.v in 25% albumin) increased plasma HO-1 protein concentration by 4–5 fold and HO-1 activity by ~15 fo...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Bharucha, Adil E., Kulkarni, Anuja, Choi, Kyoung Moo, Camilleri, Michael, Lempke, Mary, Brunn, Gregory J., Gibbons, Simon J., Zinsmeister, Alan R, Farrugia, Gianrico
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906143/
https://ncbi.nlm.nih.gov/pubmed/19956091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2009.221
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados