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EFFECTS OF ASPIRIN& SIMVASTATIN AND ASPIRIN, SIMVASTATIN & LIPOIC ACID ON HEME OXYGENASE-1 IN HEALTHY HUMAN SUBJECTS

BACKGROUND: Heme-oxygenase 1 (HO-1) degrades heme and protects against oxidative stress. In vitro and animal models suggest that HO-1 is beneficial in several diseases (e.g., post-operative ileus, gastroparesis, acute pancreatitis, and colitis). However the only drugs (i.e., hemin and heme arginate)...

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Bibliographische Detailangaben
Hauptverfasser: Bharucha, Adil E., Choi, Kyoung Moo, Saw, Jessica, Gibbons, Simon J., Farrugia, Gianrico, Carlson, David, Zinsmeister, Alan R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177447/
https://ncbi.nlm.nih.gov/pubmed/25093998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nmo.12404
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